Prof. Howard Cedar
, Developmental Biology & Cancer Research, IMRIC
Harry and Helen L. Brenner Professor of Molecular Biology
My research at IMRIC actually began when I entered NYU in 1964. That's when I started thinking about genetics and the genetic ‘book.’
For the last 50 years, scientists have been asking “What's the machinery for translating the genetic information? What's in that genetic ‘book’ and how does it all work?” Well, as it turns out that it's not about the book, but rather how that book is read. DNA has letters and sentences just like any other text, and at IMRIC we are learning how to chemically circle or underline the text to turn it on or off. That's DNA methylation. This is what our IMRIC team is now doing in its collaboration with Dr. Moshe Szyf at McGill University in Montreal.
It’s an important step in understanding human development, and a very important breakthrough in the treatment and diagnosis of genetic diseases.
1964: Massachusetts Institute of Technology
1970: M.D. and Ph.D., New York University
Winner of the prestigious medical award, Haim Cedar, in a message to the decision makers: "The government must allocate more money to research – it's the inexpensive method for curing"
Calcalist, 20 April, 2011 - The 2011 Gairdner Award was granted to Israeli professors Haim Cedar and Aharon Razin for their contribution to the treatment of cancer. The president and chairman of the Gairdner Foundation came to Israel to grant the prize and are convinced that they will locate additional candidates in the future: "Israelis just have the right DNA"
By JENNY HAZAN, CJN Israel Bureau
Thursday, 28 April 2011
TEL AVIV — Five representatives from the Gairdner Foundation of Canada toured Israel earlier this month and met with the Israeli recipients of this year’s prestigious Canada Gairdner International Awards.
World-renowned Hebrew University biochemists Prof. Howard (Chaim) Cedar and emeritus Prof. Aharon Razin were pleased to hear predictions late last week that they would likely win the 2013 Nobel Prize in the fields of medicine or chemistry.
Epigentics is the study of how chemical changes caused by our environment can alter our gene expression – without altering DNA structure. Bird, Cedar and Razin have focused their work on how these signals and changes can now be used for therapies and understanding diseases - epigenetics can no longer just be dismissed as an phenomenon.