Researchers

No one is immune to the effects of the world’s most pressing medical challenges. And none of these challenges are immune to the brilliance and dedication of IMRIC’s researchers. Get to know them a little better by checking out their bios.

A (3) | B (4) | C (2) | D (2) | F (1) | G (1) | H (1) | I (1) | J (1) | K (6) | L (3) | M (2) | O (1) | P (3) | R (2) | S (3) | W (1) | Y (3)

Prof. Baruch Minke

I am a native Israeli and grew up here. Much of my academic life has been at The Hebrew University of Jerusalem. It is here that I pursued my B.Sc. in biology, Masters in physiology and PhD in biophysics.

After my PhD I continued my studies in the United States at Purdue University. Here I specialized in genetic dissection of signal transduction systems.

My investigations have created a new field of research. I identified a new type of ion channel, the TRP channel, as a result of my studies on phototransduction and vision in fruit flies (Drosophila melanogaster). I investigated the biophysical and biochemical properties of TRP channels in fruit fly eyes, and identified phospholipase C as a crucial component of the Drosophila TRP signaling pathway. The principles that I found are common to numerous sensory systems, including nociception, thus laying the foundation for the study of the molecules that underlie mechanisms of pain.

Today my research along with other scientists continues to make waves worldwide. Through these investigations it has become evident that TRP channels govern many of the human body's regulatory processes. These proteins are involved not only in fly vision but also in initiating the sensation of pain, temperature, and taste, and even in hereditary neurological diseases.

Prof. Ofer Mandelboim

Before becoming an IMRIC researcher, I studied at the Weitzman Institute and did my post doctoral work at Harvard. I was delighted to be accepted at Hebrew University. I enjoy doing research, and at IMRIC, I am working with a team of outstanding students in collaboration with Dr. Plummer and his team to isolate the NK cells that target AIDS and prevent its spread.

But it goes beyond that.

This IMRIC collaboration is leading us to make some important discoveries in other areas on the way to finding a cure for AIDS. Once we learn how the process works, we can start isolating virus-specific NK cells to target a whole range of viruses, like influenza, and prevent their spread.