No one is immune to the effects of the world’s most pressing medical challenges. And none of these challenges are immune to the brilliance and dedication of IMRIC’s researchers. Get to know them a little better by checking out their bios.
My work at IMRIC stems from my childhood interest in science. As a child I would attend after-school activities at The Weizmann Institute near my house, which got me interested in science. This continued through high school. After my military service, I began to study biology and oceanography, but ultimately I found the study of genetics and genetic manipulation really cool.
I did my Masters work at Hebrew University on genetic regulation of viruses and later focused on cell biology. At IMRIC, my team and I are studying age-related diseases, trying to find out how to prevent these diseases from occurring by preventing protein aggregation, a key factor in the development of age-related diseases.
Ultimately, we hope that our IMRIC research will not only translate into slowing down the degenerative process, but prevent it entirely.
My research at IMRIC actually began when I entered NYU in 1964. That's when I started thinking about genetics and the genetic ‘book.’
For the last 50 years, scientists have been asking “What's the machinery for translating the genetic information? What's in that genetic ‘book’ and how does it all work?” Well, as it turns out that it's not about the book, but rather how that book is read. DNA has letters and sentences just like any other text, and at IMRIC we are learning how to chemically circle or underline the text to turn it on or off. That's DNA methylation. This is what our IMRIC team is now doing in its collaboration with Dr. Moshe Szyf at McGill University in Montreal.
It’s an important step in understanding human development, and a very important breakthrough in the treatment and diagnosis of genetic diseases.