vlog #1: Lorna Moll, Post Doctoral Fellow
I am very excited to share with you, the behind the scenes of our lab’s recent breakthrough. Together our lab, led by Prof. Ehud Cohen here at IMRIC, and the start-up company TyrNovo discovered a potential treatment of brain diseases. We found that TyrNovo’s unique compound, named NT219, selectively inhibits the process of aging in order to protect the brain from neurodegenerative diseases, like Alzheimer’s and Huntington’s disease, without affecting lifespan.
While this is the first step in what is still a long line of investigations, it is extremely exciting for us. Check out my first vlog explaining the research and what’s to come.
Bio: After I finished my B.Sc. at the University of Cologne, Germany, I joined the lab of Prof. Ludwig Eichinger where I investigated the expression pattern of Dictyostelium discoideum after infection with Mycobacterium marinum via cDNA Microarrays. During my PhD thesis I worked in the lab of Dr. Markus Schubert at the University of Cologne and got interested in the connection between the insulin/IGF1R signalling pathway and neurodegenerative diseases like Alzheimer´s disease. I analysed the function of the downstream transcription factor FoxO1 of the insulin/IGF-1R signaling cascade in Alzheimer´s disease. For my post-doctoral research in the group of Dr. Ehud Cohen I continue to study the role of DAF-16/FoxO mediated protection against age-associated proteotoxicity in the nematode Caenorhabditis elegans.